Based on his post yesterday, it seems like Mark Pilgrim has left the building. He talks about finding a new hobby aside from the web design and development that have occupied his time for several years now.
A shame, I feel, having only recently discovered his work on accessibility and web design, and finding it extremely valuable. I can't recommend highly enough his online book Dive Into Accessibility. His websites have been a model for me in the ongoing redesign of my site.